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Paracetamol, the active component of Pracetam®, is one of the safest and most reliable remedies used worldwide for the past 40 years in human medicine. CEVA offers you Pracetam®, a paracetamol solution developed for animal health. Pracetam® is an effective solution for treatment of fever during flu syndromes or acute respiratory disorders, together with other applications that we’ll explore further on.
Parameters | Administration of drinkable |
---|---|
T 1/2 absorption | 1 hr 30 min |
T 1/2 absorption | 4 hrs 30 min |
C max | 6.99 μg/ml |
T max | 4 hrs |
F (bioavailability) | 89% |
A pharmacokinetic study carried out with Pracetam® 20% Oral Solution has shown a very rapid absorption of paracetamol during its administration to pigs by the oral route in their drinking water. The possibility of obtaining nearly maximum concentration peak (Cmax) is an additional factor for increased efficacy.
A study conducted at Saint Gilles INRA station showed that Pracetam® has no effect on gastric emptying. The test results were convincing, as the evacuation of test meals occurred without a latency phase and no significant difference was noted concerning the half-emptying time.
COMPARATIVE TABLE | ||||
---|---|---|---|---|
PRACETAM® | ACETYLSALICYLIC ACID | SODIUM SALICYLATE | KETOPROFEN | MELOXICAM ORAL |
CONTENT | ||||
10%, 20%, 40% | Variable | Variable | Variable | 15% |
WITHDRAWAL PERIOD (PIGS) | ||||
0 day | Variable | 0 day | Variable | 5 days |
DOSE | ||||
Unique | Very variable: | Unique | Unique. | Short treatment: |
TOXICITY / RISKS (ULCERS) | ||||
No risk of ulcers. | Ulcerogenic. | Ulcerogenic. | Very ulcerogenic. | Do not use in case of risk |
BLOOD COAGULATION | ||||
No anti-coagulation effect. | Do not use in case of hemorrhagic risk. | Do not use in case of hemorrhagic risk. | Do not use in case of hemorrhagic risk. | Do not use in case of hemorrhagic risk. |
REPRODUCTIVE TOXICITY | ||||
Safe for pregnant and lactating sows at 3 times the dose. | The use is not recommended during pregnancy and lactation. | The use is not recommended during pregnancy and lactation. | The use is not recommended during pregnancy. | Can be used during pregnancy and lactation. |
SOLUBILITY | ||||
Soluble (dosing pump set at 3% or 5% for the oral solution and 5% for the powder) | Not soluble | Soluble | Soluble | Suspension for individual treatment (not soluble). |
ASSOCIATION | ||||
Possible with antibiotics or NSAIDs if necessary. | Concurrent use with other NSAIDs or nephrotoxic drugs is not recommended. | Concurrent use with other NSAIDs or nephrotoxic drugs is not recommended. | Concurrent use with other NSAIDs or nephrotoxic drugs is not recommended. | Concurrent use with other NSAIDs or nephrotoxic drugs is not recommended. |
USES | ||||
pain Inflamation fever | pain Inflamation fever | pain Inflamation fever | pain Inflamation fever | pain Inflamation fever |